Steroid Hormones and Cell Cycle Regulation
From the tissue culture dish to genetically modified mice, this volume explores the long recognised role of steroid hormones in regulating cell proliferation and differentiation. Many striking effects of steroid hormones are apparent during development and neoplasia and these topics are covered extensively. Several chapters address the pharmacological uses of steroid and related hormones, their analogues and antagonists in controlling growth of endocrine cancers. This book also highlights the complex role of cross talk between steroid hormones and signals initiated at the cell surface in the regulation of cell cycle in hormone responsive tissues.
| Author: |
Kerry L. Burnstein |
| ISBN: |
1402070489 |
| Publisher: |
Kluwer Academic Publishers |
| Binding: |
Hardcover |
| Year Published: |
June 2002 |
| No. of Pages: |
280 |
| Contents: |
List of Contributors
Preface
1. Mechanisms of Steroid Receptor and Growth Factor Cross Talk
2. Regulation of G1 to S Phase Transition by Adhesion and Growth Factor Signaling
3. Control of Mammary Epithelial Cell Proliferation: The Unique Role of the Progesterone Receptor
4. Estrogen/Estrogen Antagonist Regulation of the Cell Cycle in Breast Cancer Cells
5. Prostate Gland Development and Estrogenic Imprinting
6. Androgen Mediated Regulation of the G1-S Transition in Prostate Cancer
7. Steroid Hormone and Growth Factor Interaction in the Regulation of Cell Cycle Progression
8. Glucocorticoid Regulation of Cell Proliferation
9. Vitamin D Regulation of Cell Cycle and Differentiation in MyeloidCells
10. Anti proliferative Effect of Vitamin D in Prostate Epithelial Cells
11. Regulation of the Cell Cycle by Peroxisome Proliferator-Activated Receptor Gamma (PPARÉ)
12. Regulation of Glucocorticoid Receptor Function During the Cell Cycle
13. Interaction of Cell Cycle Regulatory Proteins with theAndrogen Receptor
14. Cyclin Dependent Kinase Regulation of Estrogen Receptor Phosphorylation and Transcriptional Activation
Index. |
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