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Adrenal Disorders
In Adrenal Disorders, a panel of distinguished physicians and researchers select the most relevant new findings and integrate them into the existing body of clinical knowledge on adrenal pathologies. The book includes important reviews of disturbances in cortisol homeostasis, and new concepts regarding adrenal tumors and hereditary adrenal diseases. Also discussed are mineralocorticoids and the syndromes of mineralocortoid excess and aldosterone synthase deficiency. Authoritative and insightful, Adrenal Disorders provides physicians and scientists with a comprehensive, state-of-the-art practical guide to the devastating diseases of the adrenals that are so often difficult to diagnose and treat.
| Author: |
Andrew N. Margioris, George P. Chrousos |
| ISBN: |
0896034119 |
| Publisher: |
Humana Press |
| Binding: |
Hardcover |
| Year Published: |
April 2001 |
| No. of Pages: |
416 |
| Contents: |
Part I. The Adrenal Gland: Physiology
* Ontogeny of the Hypothalamo-Pituitary-Adrenal Axis
* Adrenal Organogenesis and Steroidogenesis: Role of Nuclear Nuclear Receptor Steroidogenic Factor-1, DAX-1, and Estrogen Receptor
* Reappraisal of Adrenal Zonation Theories Based on the Differential Regulation of Apoptosis
* Pharmacology of Glucocorticoids: An Overview
* Glucocorticoid Catabolism and the 11_-Hydroxysteroid Dehydrogenase System
* Androgens of Adrenal Origin
* Structure, Function, and Regulated Expression of the Steroidogenic Acute Regulatory (StAR) Protein: Molecular Insights into the Acute Seroidogenic Response of the Adrenals and Gonads to Trophic Stimulation
* Regulation of Adrenocortical Function by the Sympathoadrenal System: Physiology and Pathology
* Interleukin (IL)-1 Family of Cytokines and Corticotropin-Releasing Hormone (CRH) in the Adrenal Gland
Part II. The Adrenal Gland: Pathophysiology
* Overview of Hyper- and Hypocortisolism
* ACTH Resistance, Constantine Tsigos. Syndromes of Ectopic ACTH Secretion: Recent Pathophysiological Aspects
* Clinical Presentations and Diagnosis of Cushing's Syndrome
* The Desmopressin Test: A New Tool in the Functional Evaluation of the Pituitary-Adrenal Axis Patients with Cushing's Syndrome
* PseudoCushing Syndromes
* Adrenocortical Tumors and Oncogenes
* Management of Adrenal Cancer
* Adrenal Incidentalomas
* Congenital Adrenal Hyperplasia: 21-Hydroylase Deficiency
* Steroid 11_-Hydroxylase Deficiency
* Micronodular Adrenal Disease and the Syndrome of Myxomas, Spotty Skin Pigmentation, and Endocrine Overactivity
* Congenital Lipoid Adrenal Hyperplasia
* Congenital Adrenal Hypoplasia
* The HPA Axis and HIV Infection
* Hypothalamic-Pituitary-Adrenal Axis and Obesity
* Aldosterone Synthase Deficiency
* Mineralocorticoid Excess Syndromes
* Pheochromocytoma: Progress in Diagnosis, Therapy, and Genetics |
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| About The Author: |
Andrew N. Margioris,
(University of Crete School of Medicine, Crete, GREECE)
George P. Chrousos,
(National Institute of Child Health & Human Development, Bethesda, MD) |
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