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Aging, Osteoporosis, and Dental Implants
Many partially or completely edentulous elderly patients are affected by osteoporosis. This book explores the relationship between osteoporosis and osseointegration and offers treatment strategies for patients who require implant-prosthodontic rehabilitation. Clinical consequences of compromised bone quality are discussed in depth. Bone formation and wound healing are described in detail.
| Author: |
George Zarb, Ulf Lekholm, Tomas Albrektsson, Howard Tenenbaum |
| ISBN: |
0867154071 |
| Publisher: |
Quintessence Publishing |
| Binding: |
Hardcover |
| Year Published: |
March 2002 |
| No. of Pages: |
280 |
| Illustrations: |
184 |
| Back Cover: |
Preface The late 20th century has brought to many patients the ultimate gift: the luxury of aging. Implicit in this gift of longevity, however, is the predicament of likely and variable adverse changes in body tissues. The biochemical sequelae of aging frequently include the risk of osteoporosis, which can take its toll on an elderly patient’s way of life. Specific oral morphologic and functional sequelae of aging are well documented in the dental literature, but those of osteoporosis are not. Presumed correlations between age, systemic osteoporosis, periodontal disease, tooth loss, and changes in the quantity and quality of jawbone have been reported. Nonetheless, hierarchies of therapy for partially and completely edentulous patients, which are infrequently evidence-based, are far from compelling. Consequently, the frequency of prescription of implant-supported prostheses for elderly patients who are currently or potentially osteoporotic demands a better understanding of the relationship between osteoporosis and the induced osseointegration response in both the short and long terms.
To advance dialogue in this area, the University of Toronto sponsored a Symposium on Aging, Osteoporosis, and Dental Implants in November 2000. The proceedings contained in this book attempt to reconcile current clinical understanding of aging, with or without osteoporosis, with overall dental patient management strategies, placing particular emphasis on the introduction and maintenance of the osseointegrated response.
Current public concern about regenerative medicine and genetic engineering is a timely reminder of dentistry’s small, if indispensable, role in overall health concerns. A utopian vision of organ stocks and biotechnology to guarantee longevity remains an integral part of a miracle medicine scenario. However, the glittering promise of such research continues to intimidate many citizens, who have placed greater demands for vigilance, restraint, and integrity on scientists and governments.
Luckily, our profession has not been unduly burdened with such tricky ethical questions as those associated with genetics and organ transplantations. We have been in the |
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| Contents: |
Section 1: Biologic and Bioengineering Considerations for Prescribing Prosthetic Implants * Mesenchymal Stem Cells and Their Involvement in Bone Remodeling, Repair, and Regeneration * The Concept of Bone Quality in Osteoporosis * Mechanical Factors and Osseointegration: Influence of Implant Design * Choosing a Prosthesis for Total Hip Replacement: Biologic and Biomechanical Considerations
Section 2: The Oral Surgical Experience * Osseointegration Surgery: Host Determinants and Outcome * Compromised Alveolar Bone Quality in Edentulous Jaws * Compromised Jawbone Quantity and Its Influence on Oral Implant Placement * Surgical Site Development in the Partially Edentulous Patient * Strategies for Bone Regeneration and Osseointegration in Completely Edentulous Patients
Section 3: The Prosthodontic Experience * Epidemiologic Considerations with Oral Implants for Elderly Patients * Significance of Tooth Loss in the Elderly Patient * The Advent of Osseointegration and Its Impact on Prosthodontic Management of Edentulous Patients * Load Transfer, Tissue Reaction, and Oral Function in Mandibular Implant-Retained Overdentures * Implant Prosthodontic Treatment Outcomes in Elderly Patients
Section 4: Biologic Perspectives Related to Osseointegration in the Elderly * Regulation of Biomineralization by Bone Proteins and Their Assembly into Extracellular Matrices: Implications for Implant * Effects of Postmenopausal Osteoporosis on the Mandible * Temporal Relationship Between Expression and Synthesis of Bone Matrix Proteins During Osteogenesis * Cigarette Smoking and Osseointegration * Potential Role of Cigarette Smoke–Derived Aryl Hydrocarbons in Failed Osseointegration |
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